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The Pharmacokinetics and Skin Changes in Rabbit on Selamectin Solution
Yu Chuan,
Liu Penggang,
Yang Gang,
Wu Qiang
Issue:
Volume 5, Issue 2, June 2021
Pages:
32-37
Received:
23 March 2021
Accepted:
10 April 2021
Published:
20 April 2021
Abstract: Background: It found that many antiparasitic drugs have a good treatment effect on the pets skin diseases. whether selamectin solutions have a bad effect on skin tissues needs more research. Objective: In order to investigate the effect of selamectin solution on skin changes in rabbit. Method: the skin of rabbit was given different doses of selamectin solution, then the quantity of per unit area of hair follicles and sebaceous glands and the morphology structure of them and the changes of skin thickness, epidermis thickness and dermis thickness were researched through routine paraffin sections and H. E, Evg, Masson’s, Pas, Toluidine blue staining and Image Pro Plus6.0. The concentration of blood and urine were measured by High Performance Liquid Chromatography after administration. Results: The thickness of skin, per unit of hair follicles and sebaceous glands all had an obviously increasing trend with the increasing of doses. 1 day later, the blood and urine concentration of the selamectin and the metabolite avermectin all were in highest. Many selamectin solution were excluded in the form of prototypes and many were in avermectin. There were a higher blood concentration and metabolite avermectin until 72h. Conclusion: The skin appearance changes were insignificant while the skin thickness and accessory organs increased obviously in microscope after given more selamectin. In 24h, the blood and urine concentration all were in highest. This study, which discussed the influences by selamectin solution in rabbit skin and the pharmacokinetics, was to provide the basis for the deeper study of Antiparasitic drugs effects on pet skin diseases.
Abstract: Background: It found that many antiparasitic drugs have a good treatment effect on the pets skin diseases. whether selamectin solutions have a bad effect on skin tissues needs more research. Objective: In order to investigate the effect of selamectin solution on skin changes in rabbit. Method: the skin of rabbit was given different doses of selamec...
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Effects of the Combination of Rice By-Products (Fermented Straw and Bran) and Legumes (Leucaena and Gliricidia Leaves) on the Growth Rate of Male Bali Cattle
Carlito de Araújo Mali Code,
Graciano Soares Gomes,
Alberto Agostinho Pereira da Costa Joao
Issue:
Volume 5, Issue 2, June 2021
Pages:
38-41
Received:
25 April 2021
Accepted:
20 May 2021
Published:
27 May 2021
Abstract: To increase the quality of dry rice straw and meet the needs of nutritional requirement for livestock, availability and technology should be considered to come up with an improve that is easy and inexpensive feeding material. The research aims to find out the effects of the combination of rice by-products (dry fermented straw and bran) with legumes (Leucaena and Gliricidia leaves) in increasing the growth of Bali cattle. This research was conducted at the Maliana Administrative, Bobonaro Municipality, from August 28, 2019 to November 17, 2019. In this research, five (5) male and growing beef cattle were used. This research method used the experimental method with Latin Square Design consisting of five treatments and five replications. The feed combinations or treatments used for beef cattle ration formulations, were: T1 is composed of 40% fermented rice straw, 20% rice bran, 10% Gliricidia and 30% Leucaena; T2 is composed of 55% fermented rice straw, 10% rice bran, 20% Gliricyda and 15% leucaena; T3 is composed of 50% fermented rice straw, 5% rice bran; 35% Gliricyda, and 15% leucaena; T4 is composed of 45% fermented rice straw, 15% rice, 30% Gliricyda, and 10% leucaena; T5 is composed of 30% fermented rice straw, 25% rice, 5% Gliricyda, and 40% leucaena. The variables observed were feed intake (kg), feed conversion and animal body weight (kg). Data analysis show that no significant effect (P> 0.05) on ration consumption but had a significant effect (P<0.05) on body weight gain and feed conversion of all experimental beef cattle used in the study. The result of comparison of mean show that the treatment T3 can accelerate growth and improve feed conversion of male beef cattle in their growth phase.
Abstract: To increase the quality of dry rice straw and meet the needs of nutritional requirement for livestock, availability and technology should be considered to come up with an improve that is easy and inexpensive feeding material. The research aims to find out the effects of the combination of rice by-products (dry fermented straw and bran) with legumes...
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Pre Extension Demonstration of Adapted Oat Varieties at Midland Areas of Guji Zone, Southern Oromia
Basha Kebede,
Dembi Korji,
Girma Amare
Issue:
Volume 5, Issue 2, June 2021
Pages:
42-46
Received:
22 April 2021
Accepted:
15 June 2021
Published:
28 June 2021
Abstract: Ethiopia is leading Africa in number of livestock though production and productivity of livestock at household level is low. In midland districts of Guji zone there was lack of improved forage varieties to feed livestock so that number of livestock ownership by household head is becoming low. To solve this problem adaptation study of oat varieties was conducted in the midlands. Since adaptation study did not ensure the accessibility of oat varieties for target area this demonstration was initiated to reach many farmers and agro-pastorals to evaluate improved oat varieties, to increase the knowledge and skills and to identify farmers/agro pastorals preference on improved oat varieties. Activity was done during 2019 and 2020 year and two improved oat varieties called Jasari and ILRI 5453 were demonstrated on 10mx10m areas of 8 experimental farmers and 7 agro-pastorals at Adola Rede and Wadera district respectively. Training, exchange visit and mini field day were used to increase farmers’ and agro-pastorals’ knowledge and skills on oat production. Observation, measurement, interview and focus group discussion were used to collect the data. The collected data was analyzed by t test, mean and narration form. The result of this demonstration showed that more seed yield (37.47qt/ha), high dry biomass (2.02t/ha) and more number of tillers (7.4) was obtained from ILRI 5453 than Jasari variety which gave a seed yield of 31.47qt/ha, 1.58t/ha dry biomass and5.8 number of tillers. Both varieties gave good seed yield at Wadera than Adola Rede district. This showed that oat production was more preferable at agro-pastoral area. T-test showed that there was significant difference at (1%) in seed yield and dry biomass between demonstrated varieties. Demonstrated oat varieties were early matured and hence compatible for double cropping. Experimental farmers and agro-pastorals mentioned that yield, fresh biomass and dry biomass of oat were used for livestock feeding. It was palatable for cattle during vegetative stage and after harvesting so that oat production helped farmers and agro-pastorals both during wet and dry season feeding. ILRI 5453 was selected by farmers and agro-pastorals based on its yield, dry biomass and number of tillers. Therefore, ILRI 5453 oat was recommended for further promotion at midlands and agro-pastorals of Guji zone.
Abstract: Ethiopia is leading Africa in number of livestock though production and productivity of livestock at household level is low. In midland districts of Guji zone there was lack of improved forage varieties to feed livestock so that number of livestock ownership by household head is becoming low. To solve this problem adaptation study of oat varieties ...
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